Sharpcontrol can control and save JPEG and uncompressed tiff files.
Edit By BS Editor: sharpcontrol used an Algorithm that is different from the USM found in most mainstream packages. you can open an image, drag the preview rectangle to any place and play with parameters and see a real time result of the sharpening inside the preciew rectangle. the algorithm has 5 free parameters.

Alternatively, the software also allows one to Batch process a number of images.

Sharpcontrol can control and save JPEG and uncompressed 3*8 and 3*16 bit tiff files. you can free download SharpControl 1.1 now.